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Anti-Sclerostin SOST Antibody

Boster Bio Anti-Sclerostin SOST Antibody catalog # A03551. Tested in WB, ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Sclerostin; SOST; UNQ2976/PRO7455/PRO7476

Gene Name

SOST

UniProt

Q9BQB4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from Sclerostin . at AA range: 130-210

Clonality

Polyclonal

Tissue Specificity

Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level) .

Applications

WB, ELISA, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

24031 MW

Gene Name Synonym

Sclerostin

Subcellular Location

Secreted, extracellular space, extracellular matrix

Protein Name

Sclerostin

Isotype

IgG

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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