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Anti-Synuclein-gamma SNCG Monoclonal Antibody

Boster Bio Anti-Synuclein-gamma SNCG Monoclonal Antibody catalog # A03523. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Gamma-synuclein; Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR; SNCG; BCSG1, PERSYN, PRSN

Gene Name

SNCG

UniProt

O76070

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of Synuclein-γ expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 1H1D2

Tissue Specificity

Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.

Applications

WB, IHC, IF, ELISA

Purification

Protein A purified

Concentration

1 mg/mL

Form

Liquid

Function

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity) . May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity) . .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

13331 MW

Gene Name Synonym

Gamma-synuclein

Subcellular Location

Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.

Contents

Purified antibody in PBS containing 0.03% sodium azide.

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