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Anti-POMGNT1 Antibody

Boster Bio Anti-POMGNT1 Antibody catalog # A03489. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1; POMGnT1;2.4.1.-

Gene Name

POMGNT1

UniProt

Q8WZA1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human POMGNT1 (NP_060209.3) .

Clonality

Polyclonal

Tissue Specificity

Constitutively expressed. An additional weaker band is also detected in spinal cord, lymph node, and trachea. Expressed especially in astrocytes. Also expressed in immature and mature neurons.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins (PubMed:11709191, PubMed:27493216) . Catalyzes the synthesis of the GlcNAc (beta1-2) Man (alpha1-) O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties (PubMed:11709191, PubMed:27493216) . Is specific for alpha linked terminal mannose and does not have MGAT3, MGAT4, MGAT5, MGAT7 or MGAT8 activity.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

75252 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

Subcellular Location

Golgi apparatus membrane

Protein Name

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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