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Anti-APC1 (phospho-S688) ANAPC1 Antibody

Boster Bio Anti-APC1 (phospho-S688) ANAPC1 Antibody catalog # A03471S688. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Anaphase-promoting complex subunit 1; APC1; Cyclosome subunit 1; Mitotic checkpoint regulator; Testis-specific gene 24 protein; ANAPC1; TSG24

Gene Name

ANAPC1

UniProt

Q9H1A4

Host

Rabbit

Reactivity

Human

Immunogen

Synthetic phosphopeptide derived from human APC1 around the phosphorylation site of Serine 688

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

216500 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Anaphase-promoting complex subunit 1

Protein Name

Anaphase-promoting complex subunit 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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