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Anti-NADP-dependent malic enzyme ME1 Antibody

Boster Bio Anti-NADP-dependent malic enzyme ME1 Antibody (Catalog # A03449) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

ME1, also known as NADP-ME, MES or HUMNDME, may play an important role as a housekeeping protein within the cell (1) . ME1 is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family (2) . It is expressed ubiquitously with highest expression in liver and white adipose tissue. ME1 functions as an NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (3) . The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles (3,4) . ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet (5) .

Synonyms

MES, HUMNDME, NADP-dependent malic enzyme, Malic enzyme 1, NADP-ME

Gene Name

ME1

UniProt

P48163

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

ME1 antibody is human, mouse and rat reactive. ME1 antibody is predicted not to cross-react with ME2.

Immunogen

ME1 antibody was raised against a 16 amino acid peptide near the amino terminus of human ME1. The immunogen is located within the first 50 amino acids of ME1.

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues tested including liver, placenta and white adipose tissue.

Applications

ELISA, WB, IHC-P

Field of Research

Homeostasis

Purification

ME1 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Storage Conditions

ME1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Observed Molecular Weight

64150 MW

Gene Name Synonym

Malic enzyme 1, NADP (+) -dependent, cytosolic

Subcellular Location

Cytoplasm

Protein Name

Malic enzyme 1, NADP (+) -dependent, cytosolic

Isotype

IgG

Contents

ME1 Antibody is supplied in PBS containing 0.02% sodium azide.

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