Anti-ATOX1 Antibody
Boster Bio Anti-ATOX1 Antibody catalog # A03421-1. Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
Antioxidant 1 (ATOX1) is a copper chaperone to regulate copper homeostasis in cell. In the cytosol, ATOX1 always binds to copper and transfer to ATPase proteins in the trans-Golgi network, thereby promoting copper supply to various copper-dependent oxidereductases matured within the secretory vesicles (PMID: 28294521) . Also, the protein could protect cells against oxidative damage and the expression levels of ATOX1 may help to the inflammatory response and antioxidant defense, even to modulate response to the cancer (PMID: 27472369) . ATOX1 plays an important role in the physiology of the human central nervous system , and it's highly expressed in the cerebral cortex and hippocampus (PMID: 30545441) . Either cytosol or nucleus location of ATOX1 has been reported in different literations, which may be associated with cell status (PMID: 24445997; 31317143) .
Synonyms
ATX1; ATOX 1; Antioxidant 1
Gene Name
ATOX1
UniProt
O00244
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human ATOX1 recombinant protein (Position: K3-G66) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Antioxidant 1 copper chaperone
Protein Name
Copper transport protein ATOX1
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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