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Anti-CARD8 (Tucan) Antibody

Boster Bio Anti-CARD8 (Tucan) Antibody (Catalog# A03404) . Tested in WB, IHC, IP application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Caspase recruitment domain-containing protein 8; Apoptotic protein NDPP1; CARD-inhibitor of NF-kappa-B-activating ligand; CARDINAL; DACAR; Tumor up-regulated CARD-containing antagonist of CASP9; TUCAN; CARD8; KIAA0955, NDPP1

Gene Name

CARD8

UniProt

Q9Y2G2

Host

Rabbit

Reactivity

Human

Immunogen

Full-length recombinant protein of human TUCAN (CARD8)

Clonality

Polyclonal

Tissue Specificity

High expression in lung, ovary, testis and placenta. Lower expression in heart, kidney and liver. Also expressed in spleen, lymph node and bone marrow.

Applications

WB, IHC, IP

Field of Research

Apoptosis, Caspases, Cell Biology, Intracellular

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

48933 MW

Gene Name Synonym

Caspase recruitment domain-containing protein 8

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Caspase recruitment domain-containing protein 8

Isotype

Rabbit IgG

Contents

50 μ l sera

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