Anti-IL12RB1 Antibody
Boster Bio Anti-IL12RB1 Antibody catalog # A03401. Tested in WB, IF, IHC, ELISA applications. This antibody reacts with Mouse, Rat.
Product Specifications
Synonyms
Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12RB1; IL-12 receptor beta component; CD212; IL12RB1; IL12R, IL12RB
Gene Name
IL12RB1
UniProt
P42701
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant full length protein of human CD212.
Clonality
Polyclonal
Applications
WB, IF, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
73109 MW
Gene Name Synonym
Interleukin-12 receptor subunit beta-1
Subcellular Location
Membrane; Single-pass type I membrane protein.
Protein Name
Interleukin-12 receptor subunit beta-1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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