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Anti-Autophagy-related protein 9B ATG9B Antibody

Boster Bio Anti-Autophagy-related protein 9B ATG9B Antibody (Catalog # A03381) . Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG9B plays a role in autophagy and it's highly expressed in placenta and pituitary gland.

Synonyms

SONE, APG9L2, NOS3AS, Autophagy-related protein 9B, APG9-like 2, Protein sONE

Gene Name

ATG9B

UniProt

Q674R7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

ATG9B antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ATG9B. The immunogen is located within amino acids 850 - 900 of ATG9B.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in placenta (trophoblast cells) and pituitary gland. Not expressed in vascular endothelial.

Applications

ELISA, WB, ICC, IF

Field of Research

Autophagy

Purification

ATG9B Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle (By similarity) . .

Storage Conditions

ATG9B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

101019 MW

Gene Name Synonym

ATG9 autophagy related 9 homolog B (S. cerevisiae)

Subcellular Location

Cytoplasmic vesicle, autophagosome membrane

Protein Name

ATG9 autophagy related 9 homolog B (S. cerevisiae)

Isotype

IgG

Contents

ATG9B Antibody is supplied in PBS containing 0.02% sodium azide.

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