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Anti-Podocalyxin/PODXL Antibody

Boster Bio Anti-Podocalyxin/PODXL Antibody catalog # A03359-2. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Background

Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It is involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation, the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns (PMID: 17092254) .

Synonyms

PODXL; GCTM 2 antigen; GCTM-2 antigen; Gp200; PC

Gene Name

PODXL

UniProt

O00592

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human Podocalyxin/PODXL recombinant protein (Position: S25-F426) .

Clonality

Polyclonal

Applications

WB, IHC, IF, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Gene Name Synonym

Podocalyxin like

Protein Name

Podocalyxin

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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