Anti-Podocalyxin/PODXL Antibody
Boster Bio Anti-Podocalyxin/PODXL Antibody catalog # A03359-2. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It is involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers. Podocalyxin is a protein with a peptide bone of ∼55.5 kDa that undergoes a post‐translational glycosylation, the different molecular mass of podocalyxin indicates the extent and variability of glycosylation patterns (PMID: 17092254) .
Synonyms
PODXL; GCTM 2 antigen; GCTM-2 antigen; Gp200; PC
Gene Name
PODXL
UniProt
O00592
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human Podocalyxin/PODXL recombinant protein (Position: S25-F426) .
Clonality
Polyclonal
Applications
WB, IHC, IF, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Podocalyxin like
Protein Name
Podocalyxin
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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