Anti-Protein sel-1 homolog 1 SEL1L Antibody
Boster Bio Anti-Protein sel-1 homolog 1 SEL1L Antibody catalog # A03343. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Protein sel-1 homolog 1; Suppressor of lin-12-like protein 1; Sel-1L; SEL1L; TSA305; UNQ128/PRO1063
Gene Name
SEL1L
UniProt
Q9UBV2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SEL1L (NP_005056.3) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in pancreas.
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509) . Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
88755 MW
Gene Name Synonym
Protein sel-1 homolog 1
Subcellular Location
Endoplasmic reticulum membrane
Protein Name
Protein sel-1 homolog 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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