Anti-ATF7IP Antibody
Boster Bio Anti-ATF7IP Antibody catalog # A03319-1. Tested in IHC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
ATF7IP (Activating Transcription Factor 7 Interacting Protein), also known as MCAF1 (MBD1-containing chromatin-associated factor 1), is a multifunctional scaffold protein that plays a pivotal role in epigenetic regulation and transcriptional control. Functionally, ATF7IP acts as an adaptor that recruits the histone methyltransferase SETDB1 to specific genomic loci, facilitating the deposition of the heterochromatin mark H3K9me3 and silencing target genes, including retrotransposons such as LINE1. This activity is essential for maintaining genomic stability by suppressing transposable element mobilization and preventing DNA damage.
Gene Name
ATF7IP
UniProt
Q6VMQ6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human ATF7IP recombinant protein (Position: A758-P1103) .
Clonality
Polyclonal
Applications
IHC, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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