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Anti-MAX (phospho-S11) Antibody

Boster Bio Anti-MAX (phospho-S11) Antibody catalog # A03239S11. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Protein max ; Class D basic helix-loop-helix protein 4; bHLHd4; Myc-associated factor X

Gene Name

MAX

UniProt

P61244

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic phosphorylated peptide around S11 of human MAX (NP_002373.3) .

Clonality

Polyclonal

Tissue Specificity

High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

18275 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Protein max

Subcellular Location

Nucleus. Cell projection, dendrite .

Protein Name

Protein max

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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