Anti-MYL2 Monoclonal Antibody
Boster Bio Anti-MYL2 Monoclonal Antibody catalog # A03215. Tested in WB, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform ; MLC-2 ; MLC-2v; Cardiac myosin light chain 2 ; Myosin light chain 2, slow skeletal/ventricular muscle isoform ; MLC-2s/v ; Ventricular myosin light chain 2 ; MYL2 ; MLC2
Gene Name
MYL2
UniProt
P10916
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of MYL2 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 7C9
Applications
WB, ELISA
Purification
Ascitic fluid
Concentration
1 mg/mL
Form
Liquid
Function
Contractile protein that plays a role in heart development and function (By similarity) . Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) . During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity) . .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
18789 MW
Gene Name Synonym
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
Subcellular Location
Cytoplasm, myofibril, sarcomere, A band .
Contents
Ascitic fluid containing 0.03% sodium azide.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
