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Anti-PEX19/Peroxin 19 Antibody

Boster Bio Anti-PEX19/Peroxin 19 Antibody (Catalog# A03186) . Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

PEX19; HK33; PXF; OK/SW-cl.22; Peroxisomal biogenesis factor 19;33 kDa housekeeping protein; Peroxin-19; Peroxisomal farnesylated protein

Gene Name

PEX19

UniProt

P40855

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human PEX19. Immunogen sequence location: 219-268

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Organelle Proteins, Organelles, Protein Trafficking, Signal Transduction, Subcellular Markers, Tags & Cell Markers

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

32807 MW

Gene Name Synonym

Peroxisomal biogenesis factor 19

Subcellular Location

Cytoplasm. Peroxisome membrane; Lipid-anchor; Cytoplasmic side. Mainly cytoplasmic. Some fraction membrane-associated to the outer surface of peroxisomes.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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