Anti-Interleukin-1 receptor type 2 IL1R2 Antibody
Boster Bio Anti-Interleukin-1 receptor type 2 IL1R2 Antibody catalog # A03106. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; Interleukin-1 receptor type 2, membrane form; mIL-1R2; mIL-1RII; Interleukin-1 receptor type 2, soluble form; sIL-1R2; sIL-1RII; IL1R2; IL1RB
Gene Name
IL1R2
UniProt
P27930
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human IL1R2.
Clonality
Polyclonal
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45421 MW
Applications Notes
WB: 1:500-1:1000
Gene Name Synonym
Interleukin-1 receptor type 2
Subcellular Location
Isoform Short: Secreted
Protein Name
Interleukin-1 receptor type 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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