Anti-PDCL Antibody (N-term)
Boster Bio Anti-PDCL Antibody (N-term) (Catalog # A03099-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.
Product Specifications
Background
Isoform 1: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.
Synonyms
Phosducin-like protein, PHLP, PDCL, PHLOP1, PhLP1
Gene Name
PDCL
UniProt
Q13371
Host
Rabbit
Reactivity
Human
Immunogen
This PDCL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDCL.
Clonality
Polyclonal
Applications
IHC-P, WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Acts as a positive regulator of hedgehog signaling and regulates ciliary function. [Isoform 2]: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
34282 Da
Subcellular Location
Cell projection, cilium {ECO:0000250|UniProtKB:Q9DBX2}
Prediction Reactivity
Bovine, Mouse, Rat
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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