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Anti-PDCL Antibody (N-term)

Boster Bio Anti-PDCL Antibody (N-term) (Catalog # A03099-1) . Tested in IHC-P, WB application (s) . This antibody reacts with Human.

Product Specifications

Background

Isoform 1: Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers.

Synonyms

Phosducin-like protein, PHLP, PDCL, PHLOP1, PhLP1

Gene Name

PDCL

UniProt

Q13371

Host

Rabbit

Reactivity

Human

Immunogen

This PDCL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDCL.

Clonality

Polyclonal

Applications

IHC-P, WB

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Acts as a positive regulator of hedgehog signaling and regulates ciliary function. [Isoform 2]: Acts as a negative regulator of heterotrimeric G proteins assembly by trapping the preloaded G beta subunits inside the CCT chaperonin.

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

34282 Da

Subcellular Location

Cell projection, cilium {ECO:0000250|UniProtKB:Q9DBX2}

Prediction Reactivity

Bovine, Mouse, Rat

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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