Anti-Phosducin-like protein PDCL Antibody
Boster Bio Anti-Phosducin-like protein PDCL Antibody (Catalog # A03099) . Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling (1,2) . PDCL is widely expressed in normal human tissues and may participate directly in the regulation of calcium-evoked exocytosis in adrenal medullary chromaffin cells (3) . It is an ethanol-responsive modulator of heterotrimeric G proteins (4) .
Synonyms
PhLP, PHLOP1, PhLP1, Phosducin-like protein, PHLP
Gene Name
PDCL
UniProt
Q13371
Host
Rabbit
Reactivity
Human, Mouse, Rat
Cross Reactivity
PDCL antibody is human, mouse and rat reactive. At least two isoforms of PDCL are known to exist. PDCL antibody is predicted to not cross-react with other members of the PDCL protein family.
Immunogen
PDCL antibody was raised against a 16 amino acid peptide near the amino terminus of human PDCL. The immunogen is located within the first 50 amino acids of PDCL.
Clonality
Polyclonal
Applications
ELISA, WB
Field of Research
Signal Transduction
Purification
PDCL antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Form
Liquid
Function
Acts as a positive regulator of hedgehog signaling and regulates ciliary function.
Storage Conditions
PDCL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Observed Molecular Weight
34282 MW
Gene Name Synonym
Phosducin-like
Subcellular Location
Cell projection, cilium
Prediction Reactivity
Bovine
Protein Name
Phosducin-like
Isotype
IgG
Contents
PDCL antibody is supplied in PBS containing 0.02% sodium azide.
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