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Anti-PREX1 Antibody

Boster Bio Anti-PREX1 Antibody catalog # A03098. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; P-Rex1; PtdIns (3,4,5) -dependent Rac exchanger 1; PREX1; KIAA1415

Gene Name

PREX1

UniProt

Q8TCU6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from human protein at AA range: 340-420

Clonality

Polyclonal

Applications

WB, ELISA

Purification

PREX1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

186203 MW

Gene Name Synonym

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

Subcellular Location

Cytoplasm, cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.

Protein Name

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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