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Anti-ELMO1 Antibody

Boster Bio Anti-ELMO1 Antibody catalog # A03091. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Engulfment and cell motility protein 1; Protein ced-12 homolog; ELMO1; KIAA0281

Gene Name

ELMO1

UniProt

Q92556

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide, corresponding to the 81-126 of Human ELMO1.

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with a higher expression in the spleen and placenta.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

83829 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Engulfment and cell motility protein 1

Subcellular Location

Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.

Protein Name

Engulfment and cell motility protein 1

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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