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Anti-TIN2 TINF2 Antibody

Boster Bio Anti-TIN2 TINF2 Antibody catalog # A03070. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

TERF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2; TINF2; TIN2

Gene Name

TINF2

UniProt

Q9BSI4

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human TIN2/TIN2/TINF2 (NP_001092744.1) .

Clonality

Polyclonal

Tissue Specificity

Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

50023 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

TERF1-interacting nuclear factor 2

Subcellular Location

Nucleus

Protein Name

TERF1-interacting nuclear factor 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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