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Anti-COL17A1/Collagen Xvii Antibody

Boster Bio Anti-COL17A1/Collagen Xvii Antibody catalog # A03031. Tested in WB, IF, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Collagen alpha-1 (XVII) chain;180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2;120 kDa linear IgA disease antigen;120 kDa linear IgA dermatosis antigen; Linear IgA disease antigen 1; LAD-1;97 kDa linear IgA disease antigen;97 kDa linear IgA bullous dermatosis antigen;97 kDa LAD antigen;97-LAD; Linear IgA bullous disease antigen of 97 kDa; LABD97; COL17A1; BP180, BPAG2

Gene Name

COL17A1

UniProt

Q9UMD9

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human COL17A1. AA range:481-530

Tissue Specificity

Detected in skin (PubMed:8618013) . In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728) . Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves. .

Applications

WB, IF, ELISA

Purification

Immunogen affinity purified

Concentration

1 mg/mL

Form

Liquid

Function

May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

150419 MW

Gene Name Synonym

Collagen alpha-1 (XVII) chain

Subcellular Location

Cell junction, hemidesmosome. Membrane; Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

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