Anti-IL-15R alpha Antibody
Boster Bio Anti-IL-15R alpha Antibody catalog # A03016. Tested in WB, ELISA applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Interleukin-15 receptor subunit alpha; IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; CD215; Soluble interleukin-15 receptor subunit alpha; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA; IL15RA
Gene Name
IL15RA
UniProt
Q13261
Host
Rabbit
Reactivity
Human, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IL15RA. AA range:99-148
Tissue Specificity
Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures. .
Applications
WB, ELISA
Purification
Immunogen affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
28233 MW
Gene Name Synonym
Interleukin-15 receptor subunit alpha
Subcellular Location
Membrane ; Single-pass type I membrane protein . Nucleus membrane ; Single-pass type I membrane protein . Mainly found associated with the nuclear membrane.
Isotype
IgG
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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