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Anti-Ninein NIN Antibody

Boster Bio Anti-Ninein NIN Antibody catalog # A03001. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Ninein; hNinein; Glycogen synthase kinase 3 beta-interacting protein; GSK3B-interacting protein; NIN; KIAA1565

Gene Name

NIN

UniProt

Q8N4C6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human NIN (NP_891991.1) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in heart and skeletal muscle. Isoform 1 is more expressed than isoform 5.

Applications

WB, IHC

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells (PubMed:15190203, PubMed:23386061) . May also act as a centrosome maturation factor (PubMed:11956314) . May play a role in microtubule nucleation, by recruiting the gamma-tubulin ring complex to the centrosome (PubMed:15190203) . Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules (PubMed:15190203) . Required for centriole organization and microtubule anchoring at the mother centriole (PubMed:23386061) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

243249 MW

Gene Name Synonym

Ninein

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Protein Name

Ninein

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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