Anti-CCK-4 PTK7 Monoclonal Antibody
Boster Bio Anti-CCK-4 PTK7 Monoclonal Antibody catalog # A02957. Tested in WB, IHC, IF, ELISA applications. This antibody reacts with Human.
Product Specifications
Synonyms
Inactive tyrosine-protein kinase 7; Colon carcinoma kinase 4; CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7; PTK7; CCK4
Gene Name
PTK7
UniProt
Q13308
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human CCK-4 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 4F9
Tissue Specificity
Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.
Applications
WB, IHC, IF, ELISA
Purification
Ascitic fluid
Concentration
1 mg/mL
Form
Liquid
Function
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
118392 MW
Gene Name Synonym
Inactive tyrosine-protein kinase 7
Subcellular Location
Membrane ; Single-pass type I membrane protein . Cell junction . Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells.
Contents
Ascitic fluid containing 0.03% sodium azide.
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