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Anti-Caspase-4 CASP4 Antibody

Boster Bio Anti-Caspase-4 CASP4 Antibody (Catalog# A02941) . Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

CASP4; ICH2; Caspase-4; CASP-4; ICE (rel) -II; Protease ICH-2; Protease TX

Gene Name

CASP4

UniProt

P49662

Host

Rabbit

Reactivity

Human

Immunogen

A peptide derived from human Caspase-4. Immunogen sequence location: 75 - 124

Clonality

Polyclonal

Tissue Specificity

Widely expressed, with highest levels in spleen and lung. Moderate expression in heart and liver, low expression in skeletal muscle, kidney and testis. Not found in the brain.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Apoptosis, Apoptotic Markers, Cancer, Caspases, Cell Biology, Cell Death, Intracellular, Invasion/Microenvironment, Metabolism, Metabolism Processes, Pathways and Processes

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1.

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

43262 MW

Gene Name Synonym

Caspase-4

Subcellular Location

Endoplasmic reticulum membrane. Mitochondrion.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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