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Anti-PRPF8 Antibody

Boster Bio Anti-PRPF8 Antibody catalog # A02878. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Pre-mRNA-processing-splicing factor 8;220 kDa U5 snRNP-specific protein; PRP8 homolog; Splicing factor Prp8; p220; PRPF8; PRPC8

Gene Name

PRPF8

UniProt

Q6P2Q9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human PRPF8 (NP_006436.3) .

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

WB, IHC, ICC, IF, IP

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both the 5' and the 3' splice site.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

273600 MW

Gene Name Synonym

Pre-mRNA-processing-splicing factor 8

Subcellular Location

Nucleus speckle .

Protein Name

Pre-mRNA-processing-splicing factor 8

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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