Anti-PANK2 Antibody
Boster Bio Anti-PANK2 Antibody catalog # A02776-2. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
Pantothenate kinase 2 (PANK2) is an essential regulatory enzyme in coenzyme A biosynthesis. PANK2 mutations cause pantothenate kinase-associated neurodegeneration (PKAN), which leads to pigmentary retinopathy, progressive dystonia and other abnormalities (PMID:20603201) . PanK2 protein is localized to mitochondria of neurons in human brain, distinguishing it from other pantothenate kinases that do not possess mitochondrial-targeting sequences (PMID:15659606) . It has 4 isoforms produced by alternative splicing and alternative initiation.
Synonyms
Pantothenate kinase 2; mitochondrial intermediate form; mPanK2; iPanK2; hPanK2; EC:2.7.1.33
Gene Name
PANK2
UniProt
Q9BZ23
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
E.coli-derived human PANK2 recombinant protein (Position: D330-K568) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
Pantothenate kinase 2
Protein Name
Pantothenate kinase 2, mitochondrial
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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