Anti-RANGAP1 Antibody
Boster Bio Anti-RANGAP1 Antibody catalog # A02771. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ran GTPase-activating protein 1; RanGAP1; RANGAP1; KIAA1835, SD
Gene Name
RANGAP1
UniProt
P46060
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human RanGAP1 (NP_002874.1) .
Clonality
Polyclonal
Tissue Specificity
Highly expressed in brain, thymus and testis.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
GTPase activator for RAN (PubMed:8146159, PubMed:8896452, PubMed:16428860) . Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export (PubMed:8896452, PubMed:27160050) . Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export (PubMed:27160050) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
63542 MW
Applications Notes
WB: 1:500-1:2000
Gene Name Synonym
Ran GTPase-activating protein 1
Subcellular Location
Cytoplasm
Protein Name
Ran GTPase-activating protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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