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Anti-PTN12 PTPN12 Antibody

Boster Bio Anti-PTN12 PTPN12 Antibody catalog # A02762. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Tyrosine-protein phosphatase non-receptor type 12;3.1.3.48

Gene Name

PTPN12

UniProt

Q05209

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human protein

Clonality

Polyclonal

Applications

WB, ELISA

Purification

PTN12 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades (PubMed:18559503) . Dephosphorylates cellular tyrosine kinases, such as ERBB2 and PTK2B/PYK2, and thereby regulates signaling via ERBB2 and PTK2B/PYK2 (PubMed:17329398, PubMed:27134172) . Selectively dephosphorylates ERBB2 phosphorylated at 'Tyr-1112', 'Tyr-1196', and/or 'Tyr-1248' (PubMed:27134172) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

88106 MW

Gene Name Synonym

Tyrosine-protein phosphatase non-receptor type 12

Subcellular Location

Cytoplasm

Protein Name

Tyrosine-protein phosphatase non-receptor type 12

Isotype

IgG

Contents

Liquid form in PBS containing 50% glycerol, and 0.02% sodium azide.

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