Anti-MCM6 Antibody
Boster Bio Anti-MCM6 Antibody catalog # A02755. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
DNA replication licensing factor MCM6;3.6.4.12; p105MCM; MCM6
Gene Name
MCM6
UniProt
Q14566
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human MCM6.
Clonality
Polyclonal
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
92889 MW
Gene Name Synonym
DNA replication licensing factor MCM6
Subcellular Location
Nucleus. Binds to chromatin during G1 and detach from it during S phase.
Protein Name
DNA replication licensing factor MCM6
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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