Anti-POLDIP3 Antibody (N-term)
Boster Bio Anti-POLDIP3 Antibody (N-term) (Catalog # A02748-1) . Tested in IHC-P, IF, WB application (s) . This antibody reacts with Human, Mouse.
Product Specifications
Background
This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified. [provided by RefSeq].
Synonyms
Polymerase delta-interacting protein 3, 46 kDa DNA polymerase delta interaction protein, p46, S6K1 Aly/REF-like target, SKAR, POLDIP3, KIAA1649, PDIP46
Gene Name
POLDIP3
UniProt
Q9BY77
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This POLDIP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-120 amino acids from the N-terminal region of human POLDIP3.
Clonality
Polyclonal
Applications
IHC-P, IF, WB
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Observed Molecular Weight
46089 Da
Subcellular Location
Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein
Isotype
Rabbit IgG
Contents
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
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