Anti-p150 CAF1 CHAF1A Antibody
Boster Bio Anti-p150 CAF1 CHAF1A Antibody catalog # A02732. Tested in WB, ICC, IF, IP, IHC, Flow Cytometry applications. This antibody reacts with Human.
Product Specifications
Synonyms
Chromatin assembly factor 1 subunit A; CAF-1 subunit A; Chromatin assembly factor I p150 subunit; CAF-I 150 kDa subunit; CAF-I p150; hp150; CHAF1A; CAF, CAF1P150
Gene Name
CHAF1A
UniProt
Q13111
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant protein within human p150 CAF1 aa 100-300.
Clonality
Polyclonal
Applications
WB, ICC, IF, IP, IHC, Flow Cytometry
Purification
ProA affinity purified
Concentration
1 mg/mL
Form
Liquid
Function
Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
106910 MW
Gene Name Synonym
Chromatin assembly factor 1 subunit A
Subcellular Location
Nucleus
Protein Name
Chromatin assembly factor 1 subunit A
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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