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Anti-Inverted formin-2 INF2 Antibody

Boster Bio Anti-Inverted formin-2 INF2 Antibody (Catalog # A02710) . Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Background

INF2 is a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5

Synonyms

FSGS5, CMTDIE, C14orf151, C14orf173

Gene Name

INF2

UniProt

Q27J81

Host

Rabbit

Reactivity

Human

Cross Reactivity

INF2 Antibody is predicted to not cross-react with other INF1.

Immunogen

INF2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human INF2.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.

Applications

ELISA, WB

Field of Research

Cell Cycle, Cancer

Purification

INF2 Antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Severs actin filaments and accelerates their polymerization and depolymerization. .

Storage Conditions

INF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

135624 MW

Gene Name Synonym

Inverted formin, FH2 and WH2 domain containing

Subcellular Location

Cytoplasm, perinuclear region

Prediction Reactivity

Mouse, Frog

Protein Name

Inverted formin, FH2 and WH2 domain containing

Isotype

IgG

Contents

INF2 Antibody is supplied in PBS containing 0.02% sodium azide.

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