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Anti-Nkx-3.1 Monoclonal Antibody

Boster Bio Anti-Nkx-3.1 Monoclonal Antibody catalog # A02709. Tested in WB, IHC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Product Specifications

Synonyms

Homeobox protein Nkx-3.1; Homeobox protein NK-3 homolog A; NKX3-1; NKX3.1, NKX3A

Gene Name

NKX3-1

UniProt

Q99801

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of human Nkx-3.1 expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 4H4

Tissue Specificity

Highly expressed in the prostate and, at a lower level, in the testis. .

Applications

WB, IHC, IF, Flow Cytometry, ELISA

Purification

The antibody was isolated from ascitic fluid by immunoaffinity chromatography using antigens coupled to agarose beads.

Concentration

1 mg/mL

Form

Liquid

Function

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells. .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

26350 MW

Gene Name Synonym

Homeobox protein Nkx-3.1

Subcellular Location

Nucleus .

Isotype

IgG2b

Contents

Ascitic fluid containing 0.03% sodium azide.

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