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Anti-Myosin-3 MYH3 Antibody

Boster Bio Anti-Myosin-3 MYH3 Antibody (Catalog # A02697) . Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells (1) . MYH3 (myosin, heavy chain, skeletal muscle, embryonic) plays a significant role in skeletal muscle development (2) and is also essential for the proper morphology and function of the developing heart (3) . Mutations in this gene have been associated with Freeman-Sheldon syndrome and Sheldon-Hall syndrome (4) .

Synonyms

Myosin heavy chain 3, Myosin-3, Myosin heavy chain skeletal muscle embryonic, HEMHC, MYHC-EMB, MYHSE1, SMHCE

Gene Name

MYH3

UniProt

P11055

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

MYH3 antibody is human, mouse and rat reactive. MYH3 antibody is predicted to not cross-react with other members of the myosin heavy chain family.

Immunogen

MYH3 antibody was raised against a 19 amino acid peptide near the amino terminus of human MYH3. The immunogen is located within amino acids 30 - 80 of MYH3.

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal bone, thymus, placenta, heart, brain, and liver.

Applications

ELISA, WB, IHC-P

Field of Research

Homeostasis

Purification

MYH3 antibody is affinity chromatography purified via peptide column.

Concentration

1 mg/mL

Form

Liquid

Function

Muscle contraction.

Storage Conditions

Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.

Observed Molecular Weight

223905 MW

Gene Name Synonym

Myosin, heavy chain 3, skeletal muscle, embryonic

Subcellular Location

Cytoplasm, myofibril. Thick filaments of the myofibrils.

Protein Name

Myosin, heavy chain 3, skeletal muscle, embryonic

Isotype

IgG

Contents

MYH3 antibody is supplied in PBS containing 0.02% sodium azide.

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