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Anti-Caper (R199) ATP6AP2 Antibody

Boster Bio Anti-Caper (R199) ATP6AP2 Antibody catalog # A02665. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Renin receptor; ATPase H (+) -transporting lysosomal accessory protein 2; ATPase H (+) -transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryonic liver differentiation factor 10; N14F; Renin/prorenin receptor; Vacuolar ATP synthase membrane sector-associated protein M8-9; ATP6M8-9; V-ATPase M8.9 subunit; ATP6AP2; ATP6IP2, CAPER, ELDF10; HT028, MSTP009, PSEC0072

Gene Name

ATP6AP2

UniProt

O75787

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic methylpeptide derived from human Histone H3 around the methylation site of Lysine 80.

Clonality

Polyclonal

Tissue Specificity

Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

39008 MW

Applications Notes

WB: 1:500-1:1000

Gene Name Synonym

Renin receptor

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Renin receptor

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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