Anti-Ras-related protein Rap-1b RAP1B Antibody
Boster Bio Anti-Ras-related protein Rap-1b RAP1B Antibody catalog # A02596. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ras-related protein Rap-1b; GTP-binding protein smg p21B; RAP1B; OK/SW-cl.11
Gene Name
RAP1B
UniProt
P61224
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human Rap1B (NP_056461.1) .
Clonality
Polyclonal
Applications
WB, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
20825 MW
Gene Name Synonym
Ras-related protein Rap-1b
Subcellular Location
Cell membrane. Cytoplasm, cytosol. Cell junction. May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.
Protein Name
Ras-related protein Rap-1b
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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