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Anti-Ras-related protein Rap-1b RAP1B Antibody

Boster Bio Anti-Ras-related protein Rap-1b RAP1B Antibody catalog # A02596. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Ras-related protein Rap-1b; GTP-binding protein smg p21B; RAP1B; OK/SW-cl.11

Gene Name

RAP1B

UniProt

P61224

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein of human Rap1B (NP_056461.1) .

Clonality

Polyclonal

Applications

WB, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

20825 MW

Gene Name Synonym

Ras-related protein Rap-1b

Subcellular Location

Cell membrane. Cytoplasm, cytosol. Cell junction. May shuttle between plasma membrane and cytosol. Presence of KRIT1 and CDH5 is required for its localization to the cell junction.

Protein Name

Ras-related protein Rap-1b

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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