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Anti-FPR1/Fpr Antibody

Boster Bio Anti-FPR1/Fpr Antibody (Catalog# A02509) . Tested in WB, IHC, ICC, IF, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

FPR1; fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor

Gene Name

FPR1

UniProt

P21462

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human FPR1. Immunogen sequence location: 155 - 204

Clonality

Polyclonal

Tissue Specificity

Neutrophils.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Atherosclerosis, Cardiovascular, Immunology, Innate Immunity, Macrophage/Inflammation, Vascular Inflammation

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520) . Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520) . This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456) .

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

38446 MW

Gene Name Synonym

FMet-Leu-Phe receptor

Subcellular Location

Cell membrane; Multi- pass membrane protein.

Isotype

Rabbit IgG

Contents

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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