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Anti-PTPN13/PTPL1 (FAP1) Antibody

Boster Bio Anti-PTPN13/PTPL1 (FAP1) Antibody (Catalog# A02481) . Tested in IP, IHC, WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Tyrosine-protein phosphatase non-receptor type 13;3.1.3.48; Fas-associated protein-tyrosine phosphatase 1; FAP-1; PTP-BAS; Protein-tyrosine phosphatase 1E; PTP-E1; hPTPE1; Protein-tyrosine phosphatase PTPL1; PTPN13; PNP1, PTP1E, PTPL1

Gene Name

PTPN13

UniProt

Q12923

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant protein of human FAP-1 (amino acids 1279 to 1883)

Clonality

Polyclonal

Tissue Specificity

Present in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.

Applications

IP, IHC, WB

Field of Research

Cancer, Cell Biology, Cell Cycle, Kinases/Phosphatases, Protein Phosphorylation, Signal Transduction, Tyrosine Phosphatases

Concentration

0.5-1mg/mL, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Tyrosine phosphatase which regulates negatively FAS- induced apoptosis and NGFR-mediated pro-apoptotic signaling (PubMed:15611135) . May regulate phosphoinositide 3-kinase (PI3K) signaling through dephosphorylation of PIK3R2 (PubMed:23604317) . .

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Observed Molecular Weight

276906 MW

Gene Name Synonym

Tyrosine-protein phosphatase non-receptor type 13

Subcellular Location

Cytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium. Colocalizes with PKN2 in lamellipodia-like structure, regions of large actin turnover.

Protein Name

Tyrosine-protein phosphatase non-receptor type 13

Isotype

Rabbit IgG

Contents

50 μ l sera

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