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Anti-MSH3 Antibody

Boster Bio Anti-MSH3 Antibody catalog # A02455-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human.

Product Specifications

Background

MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells (PMID: 23724141, PMID:32671096) .

Synonyms

MutS homolog 3; Mismatch repair protein 1; hMSH3; DUG; DUC1

Gene Name

MSH3

UniProt

P20585

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human MSH3 recombinant protein (Position: R3-I348) .

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, IP, ELISA

Purification

Immunogen affinity purified.

Concentration

500 μg/mL

Form

Liquid

Storage Conditions

12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A02455-1

Product MSDS

https://www.bosterbio.com/msds?sku=A02455-1

Gene Name Synonym

MutS homolog 3

Protein Name

DNA mismatch repair protein Msh3

Contents

500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.

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