Anti-MSH3 Antibody
Boster Bio Anti-MSH3 Antibody catalog # A02455-1. Tested in WB, IHC, ICC, IF, IP, ELISA applications. This antibody reacts with Human.
Product Specifications
Background
MSH3 is a DNA mismatch repair (MMR) gene that heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. It undergoes frequent somatic mutation in colorectal cancers (CRCs) with MMR deficiency. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells (PMID: 23724141, PMID:32671096) .
Synonyms
MutS homolog 3; Mismatch repair protein 1; hMSH3; DUG; DUC1
Gene Name
MSH3
UniProt
P20585
Host
Rabbit
Reactivity
Human
Immunogen
E.coli-derived human MSH3 recombinant protein (Position: R3-I348) .
Clonality
Polyclonal
Applications
WB, IHC, ICC, IF, IP, ELISA
Purification
Immunogen affinity purified.
Concentration
500 μg/mL
Form
Liquid
Storage Conditions
12 months from date of receipt, -20°C as supplied. 6 months 2 to 8°C after reconstitution. Avoid repeated freezing and thawing.
Gene Name Synonym
MutS homolog 3
Protein Name
DNA mismatch repair protein Msh3
Contents
500 μg/mL antibody with PBS,0.02% NaN3, 1 mg BSA and 50% glycerol.
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