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Anti-WARS Antibody

Boster Bio Anti-WARS Antibody catalog # A02444. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Tryptophan--tRNA ligase, cytoplasmic;6.1.1.2

Gene Name

WARS

UniProt

P23381

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein of human Tryptophanyl-tRNA synthetase 1 (NP_776049.1) .

Clonality

Polyclonal

Applications

WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

53165 MW

Applications Notes

WB: 1:500-1:2000

Gene Name Synonym

Tryptophan--tRNA ligase, cytoplasmic

Subcellular Location

Cytoplasm.

Protein Name

Tryptophan--tRNA ligase, cytoplasmic

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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