Anti-Poly (rC) -binding protein 2 PCBP2 Antibody
Boster Bio Anti-Poly (rC) -binding protein 2 PCBP2 Antibody catalog # A02425. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Poly (rC) -binding protein 2; Alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2; hnRNP E2; PCBP2
Gene Name
PCBP2
UniProt
Q15366
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human hnRNP E2/PCBP2 (NP_001122383.1) .
Clonality
Polyclonal
Tissue Specificity
Detected in all tissues examined.
Applications
WB, IHC, ICC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly (rC) -binding protein. Binds also poly (rU) . Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509) . It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509) .
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
38580 MW
Gene Name Synonym
Poly (rC) -binding protein 2
Subcellular Location
Nucleus
Protein Name
Poly (rC) -binding protein 2
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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