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Anti-Poly (rC) -binding protein 2 PCBP2 Antibody

Boster Bio Anti-Poly (rC) -binding protein 2 PCBP2 Antibody catalog # A02425. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Poly (rC) -binding protein 2; Alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2; hnRNP E2; PCBP2

Gene Name

PCBP2

UniProt

Q15366

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide of human hnRNP E2/PCBP2 (NP_001122383.1) .

Clonality

Polyclonal

Tissue Specificity

Detected in all tissues examined.

Applications

WB, IHC, ICC, IF

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Concentration

1 mg/mL

Form

Liquid

Function

Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly (rC) -binding protein. Binds also poly (rU) . Negatively regulates cellular antiviral responses mediated by MAVS signaling (PubMed:19881509) . It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitination and degradation (PubMed:19881509) .

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

38580 MW

Gene Name Synonym

Poly (rC) -binding protein 2

Subcellular Location

Nucleus

Protein Name

Poly (rC) -binding protein 2

Contents

Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

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