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Anti-CD3Z Antibody (C-term)

Boster Bio Anti-CD3Z Antibody (C-term) (Catalog # A02421) . Tested in WB, Flow Cytometry application (s) . This antibody reacts with Human, Mouse.

Product Specifications

Background

T-cell receptor zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response.

Synonyms

T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3 zeta chain, CD247, CD247, CD3Z, T3Z, TCRZ

Gene Name

CD247

UniProt

P20963

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This CD3Z antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the C-terminal region of human CD3Z.

Clonality

Polyclonal

Tissue Specificity

CD3Z is expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs) (PubMed:11722641)

Applications

WB, Flow Cytometry

Field of Research

Immunology, Signal Transduction, Viral process, Host-Virus Interaction, T Cells

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

247009875090837509083

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Observed Molecular Weight

18696 Da

Subcellular Location

Cell membrane {ECO:0000250|UniProtKB:P24161}; Single-pass type I membrane protein

Prediction Reactivity

Pig

Isotype

Rabbit IgG

Contents

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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