Anti-CLIC1 Antibody
Boster Bio Anti-CLIC1 Antibody catalog # A02397. Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Chloride intracellular channel protein 1; Chloride channel ABP; Nuclear chloride ion channel 27; NCC27; Regulatory nuclear chloride ion channel protein; hRNCC; CLIC1; G6, NCC27
Gene Name
CLIC1
UniProt
O00299
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant Protein corresponding to a sequence within amino acids 42-241 of human CLIC1 (NP_001279.2) .
Clonality
Polyclonal
Tissue Specificity
Expression is prominent in heart, placenta, liver, kidney and pancreas.
Applications
WB, IHC, IF
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Concentration
1 mg/mL
Form
Liquid
Function
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
26923 MW
Gene Name Synonym
Chloride intracellular channel protein 1
Subcellular Location
Nucleus. Nucleus membrane ; Single-pass membrane protein . Cytoplasm. Cell membrane ; Single-pass membrane protein . Mostly in the nucleus including in the nuclear membrane. Small amount in the cytoplasm and the plasma membrane. Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Protein Name
Chloride intracellular channel protein 1
Contents
Rabbit IgG, 1mg/mL in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
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