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Anti-GADD34 PPP1R15A Antibody

Boster Bio Anti-GADD34 PPP1R15A Antibody catalog # A02394. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116 homolog; PPP1R15A; GADD34

Gene Name

PPP1R15A

UniProt

O75807

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from human protein at AA range: 430-490

Clonality

Polyclonal

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/mL

Form

Liquid

Function

Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

73478 MW

Gene Name Synonym

Protein phosphatase 1 regulatory subunit 15A

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side

Protein Name

Protein phosphatase 1 regulatory subunit 15A

Isotype

IgG

Contents

PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

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